Systematic (IUPAC) name | |
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5,5-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
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Clinical data | |
Pregnancy category |
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Routes of administration |
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Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Biological half-life | ? |
Excretion | ? |
Identifiers | |
CAS Registry Number | 77-32-7 |
ATC code | ?? |
PubChem | CID: 667509 |
DrugBank | ? |
ChemSpider | 580885 |
Chemical data | |
Formula | C8H12N2O2S |
Molecular mass | 200.259 |
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(what is this?) (verify) |
Thiobarbital is a drug which is a barbiturate derivative. It is the thiobarbiturate analogue of barbital.
Synthesis
It is of note that although the drug can be prepared by the above route (cf eg thialbarbital), rxn of barbital with phosphorus pentasulfide constitutes an alternative route to thiobarbital.
References
- ^ Fischer, E.; Dilthey, A. (1904). "Ueber C-Dialkylbarbitursäuren und über die Ureïde der Dialkylessigsäuren". Justus Liebig's Annalen der Chemie 335 (3): 334. doi:10.1002/jlac.19043350303.
- ^ Carrington, H. C. (1944). "45. The action of phosphorus pentasulphide on barbituric acids". Journal of the Chemical Society (Resumed): 124. doi:10.1039/JR9440000124.