Systematic (IUPAC) name | |
---|---|
(RS)-1-(1,3-benzodioxol-5-yl)-2-(ethylamino)propan-1-one
|
|
Clinical data | |
Pregnancy category |
|
Legal status |
|
Routes of administration |
Oral, nasal, IV |
Identifiers | |
CAS Number | 1112937-64-0 |
ChemSpider | 21106271 |
Chemical data | |
Formula | C12H15NO3 |
Molecular mass | 221.2524 g/mol |
|
|
|
|
(what is this?) (verify) |
Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC, bk-MDEA), is recreational designer drug classified as an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is the β-keto analogue of MDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone.[citation needed] In the United States, it began to be found in cathinone products in late 2011.[1]
Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone, but several ethylone-related deaths have been reported.[1]
Pharmacokinetics
Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps:[2]
- N-deethylation to the primary amine.
- Reduction of the keto moiety to the respective alcohol.
Legal Status
As of October 2015 Ethylone is a controlled substance in China.[3]
See also
References
- ^ a b Journal of Analytical Toxicology. doi:10.1093/jat/bkv053. Missing or empty
|title=
(help) - ^ Meyer, Markus R; Jens Wilhelm; Frank T. Peters; Hans H. Maurer (2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry". Analytical and Bioanalytical Chemistry 397 (3): 1225–1233. doi:10.1007/s00216-010-3636-5. PMID 20333362. Retrieved 19 September 2012.
- ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015.
External links
|
|
|
|