Transcriptional enhancer factor TEF-5 is a protein that in humans is encoded by the TEAD3gene.[1][2][3]
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon.[3]
References
^Jacquemin P, Depetris D, Mattei MG, Martial JA, Davidson I (Mar 1999). "Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis". Genomics55 (1): 127–9. doi:10.1006/geno.1998.5628. PMID9889009.
^Jacquemin P, Martial JA, Davidson I (Jun 1997). "Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer". J Biol Chem272 (20): 12928–37. doi:10.1074/jbc.272.20.12928. PMID9148898.
Vaudin P, Delanoue R, Davidson I et al. (1999). "TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation.". Development126 (21): 4807–16. PMID10518497.CS1 maint: Explicit use of et al. (link)
Maeda T, Mazzulli JR, Farrance IK, Stewart AF (2002). "Mouse DTEF-1 (ETFR-1, TEF-5) is a transcriptional activator in alpha 1-adrenergic agonist-stimulated cardiac myocytes.". J. Biol. Chem.277 (27): 24346–52. doi:10.1074/jbc.M201171200. PMID11986313.
Mungall AJ, Palmer SA, Sims SK et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature425 (6960): 805–11. doi:10.1038/nature02055. PMID14574404.CS1 maint: Explicit use of et al. (link)
Rual JF, Venkatesan K, Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature437 (7062): 1173–8. doi:10.1038/nature04209. PMID16189514.CS1 maint: Explicit use of et al. (link)