Eamonn F. Healy is a professor of chemistry at St. Edward's University in Austin, Texas, where his research focuses on the design of structure-activity probes to elucidate enzymatic activity. Targets include HIV-1 integrase, the c-Kit and src-abl proteins, and the metalloproteinases associated with CXCL16 shedding. He was born in NewCastle West, Co. Limerick Ireland on September 25, 1958. He received a doctorate in chemistry in 1984 from the University of Texas at Austin where he was a student of Dr. Michael J. S. Dewar. As a member of the Dewar research group he co-authored Austin Model 1, or AM1, a semi-empirical method for the quantum calculation of molecular electronic structure in computational chemistry. He appears in Richard Linklater's 2001 film Waking Life discussing concepts similar to a technological singularity and explaining "telescopic evolution." Dr. Healy is married to Shelley Bueche.
See also
Selected publications
- E.F. Healy "In Defense of a Heuristic Interpretation of Quantum Mechanics", J. Chem. Educ. 2010, 87, 559-563. doi:10.1021/ed8001545
- Eamonn F. Healy, Skylar Johnson, Charles Hauser, and Peter King "Tyrosine kinase inhibition: Ligand binding and conformational change in c-Kit and c-Abl." FEBS Lett. 2009, 583, 2899-2906 doi:10.1016/j.febslet.2009.07.051
- Eamonn F. Healy, Jonathan Sanders, Peter J. King and W. Edward Robinson, Jr "A Docking Study of L-Chicoric Acid with HIV-1 Integrase" J Mol. Graph. Model. 2009, 27, 14. doi:10.1016/j.jmgm.2008.09.011
- E. F. Healy, C. G. Wall, M.A. Fox, "Peptide Conformational Analysis using the TRIPOS Force
Field", Intl. J. Quant. Chem., 1992, 44, 543. doi:10.1002/qua.560440412
- R.A. Caldwell, H. Misawa, M.J.S. Dewar, E.F. Healy,"An Unusually Large Secondary Deuterium Isotope Effect", J. Am. Chem. Soc. 1987, 109, 6869. doi:10.1021/ja00256a061
- M.J.S. Dewar, E. G. Zoebisch, E.F. Healy, J. J. P. Stewart,"AM1: A New General Purpose
Quantum Mechanical Molecular Model", J. Am. Chem. Soc. 1985, 107, 3902. doi:10.1021/ja00299a024
- M.J.S. Dewar,, E.F. Healy, J. J. P. Stewart,"Location of Transition States in Reaction mechanisms", J. Chem. Soc., Faraday Trans. 2 1984, 80, 227. doi:10.1039/F29848000227
- M.J.S. Dewar,, E.F. Healy, "Why Life Exists", Organometallics 1982, 1, 1705. doi:10.1021/om00072a029