Grade_3_partial_androgen_insensitivity_syndrome.jpg (323 × 308 pixels, file size: 15 KB, MIME type: image/jpeg)
Summary
Description |
Left, 19-year-old man with grade 3 PAIS before initiation of androgen therapy. Right, Habitus after 3.5 years of androgen treatment. |
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Source |
Weidemann W, Peters B, Romalo G, Spindler KD, Schweikert HU. Response to androgen treatment in a patient with partial androgen insensitivity and a mutation in the deoxyribonucleic acid-binding domain of the androgen receptor. J Clin Endocrinol Metab. 1998;83:1173-1176. |
Article | |
Portion used |
Single image from an article in a medical journal. |
Low resolution? |
Resolution of this image will not affect journal subscriptions (i.e. revenue). |
Purpose of use |
Many individuals with PAIS are unaware that it is possible for them to virilize to some degree when given supraphysiological doses of testosterone. This image helps grade 3 PAIS patients make medical decisions (e.g. androgen therapy) by clearly illustrating the potential outcome of this treatment. |
Replaceable? |
PAIS is a very rare disorder, affecting approximately 1 in 100,000 births. This image is particularly rare as it documents the effects of androgen therapy on an individual with pais, and thus, it is very unlikely that it can be replaced. It is also worthy to note that this subject is sensitive, and calls for medical quality photography. |
Other information |
Sources that describe PAIS and its rarity include: (1:) Quigley CA, De Bellis A, Marschke KB, El-Awady MK, Wilson EM, French FS. Androgen receptor defects: historical, clinical, and molecular perspectives. Endocr Rev. 1995;16:271–321. (2:)Mazen I, El-Ruby M, Kamal R, El-Nekhely I, El-Ghandour M, Tantawy S, El-Gammal M. Screening of Genital Anomalies in Newborns and Infants in Two Egyptian Governorates. Horm Res Paediatr. 2010;73:438-442. |
Fair useFair use of copyrighted material in the context of Partial androgen insensitivity syndrome//en.wikipedia.org/wiki/File:Grade_3_partial_androgen_insensitivity_syndrome.jpgtrue |
Licensing
File history
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 15:49, 10 February 2017 | 323 × 308 (15 KB) | DatBot (talk | contribs) | Reduce size of non-free image (BOT - disable) | |
23:52, 19 September 2010 | No thumbnail | 656 × 627 (160 KB) | Jonathan.Marcus (talk | contribs) | {{Non-free use rationale |Article = Androgen insensitivity syndrome |Description = ''Left'', 19-year-old man with grade 3 PAIS before initiation of androgen therapy. ''Right'', Habitus after 3.5 years of androgen treatment. |Source |
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