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| C=35 | H=42 | N=2 | O=9 |
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| molecular_weight = 634.716 g/mol |
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| smiles = [H][C@]26C[C@@H](OC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1)[C@H](OC)[C@@H](C(=O)OC)[C@@]2([H])C[C@]5([H])c4[nH]c3cc(OC)ccc3c4CCN5C6 |
| smiles = [H][C@]26C[C@@H](OC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1)[C@H](OC)[C@@H](C(=O)OC)[C@@]2([H])C[C@]5([H])c4[nH]c3cc(OC)ccc3c4CCN5C6 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
Revision as of 21:05, 19 June 2020
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Clinical data | |
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Trade names | Moderil, Cinnasil, Anaprel |
Other names | methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-{[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate |
Routes of administration | oral |
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ECHA InfoCard | 100.042.232 |
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Formula | C35H42N2O9 |
Molar mass | 634.726 g·mol−1 |
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Rescinnamine, known by the brand names moderil, cinnasil, and anaprel, is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.
It is a vinca alkaloid obtained from Rauvolfia serpentina[1] and other species of Rauvolfia.[2]
References
- ^ FIFE R, MACLAURIN JC, WRIGHT JH (December 1960). "Rescinnamine in treatment of hypertension in hospital clinic and in general practice". British Medical Journal. 2 (5216): 1848–50. doi:10.1136/bmj.2.5216.1848. PMC 2098607. PMID 13699407.
- ^ Balsevich J, Constabel F, Kurz WG (1982). "Alkaloids of Vinca major cv. Variegata". Planta Med. 44 (2): 91–3. doi:10.1055/s-2007-971409. PMID 17402086.