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==See also== |
==See also== |
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* [[List of hormonal alkylating antineoplastic agents]] |
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* [[Alestramustine]] |
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* [[ |
* [[List of estrogen esters]] |
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* [[Estradiol mustard]] |
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* [[Estromustine]] |
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==References== |
==References== |
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{{Reflist|2}} |
{{Reflist|2}} |
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{{Estrogen receptor modulators}} |
{{Estrogen receptor modulators}} |
Revision as of 07:48, 17 December 2017
Clinical data | |
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Other names | Leo 275; Ro 21-8837; Estradiol 3-(bis(2-chloroethyl)carbamate) ester; Estra-1,3,5(10)-triene-3,17β-diol 3-(bis(2-chloroethyl)carbamate) ester |
Drug class | Nitrogen mustard; Alkylating antineoplastic agent; Estrogen; Estrogen ester |
Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.019.161 |
Chemical and physical data | |
Formula | C23H31Cl2NO3 |
Molar mass | 440.405 g/mol g·mol−1 |
3D model (JSmol) | |
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(what is this?) |
Estramustine (INN , USAN , BAN ) is a synthetic, steroidal estrogen and alkylating antineoplastic agent which was never marketed.[1][2] It is an estrogen ester – specifically, the C3 normustine ester of estradiol – and acts as a prodrug to estradiol and normustine in the body.[1][2] Estramustine phosphate, the C17β phosphate ester of estramustine, is marketed and used in the treatment of prostate cancer.[1][2]
See also
References
- ^ a b c J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 502–. ISBN 978-1-4757-2085-3.
- ^ a b c Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 406–. ISBN 978-3-88763-075-1.