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<!--Clinical data--> |
<!--Clinical data--> |
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| tradename = |
| tradename = Emcyt, Estracyt |
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==See also== |
==See also== |
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* [[Estradiol mustard]] |
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* [[List of hormonal cytostatic antineoplastic agents]] |
* [[List of hormonal cytostatic antineoplastic agents]] |
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* [[List of estrogen esters#Estradiol esters|List of estrogen esters § Estradiol esters]] |
* [[List of estrogen esters#Estradiol esters|List of estrogen esters § Estradiol esters]] |
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[[Category:Nitrogen mustards]] |
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[[Category:Organochlorides]] |
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[[Category:Drugs developed by Pfizer]] |
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Latest revision as of 19:57, 20 December 2023
Clinical data | |
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Trade names | Emcyt, Estracyt |
Other names | EM; EaM; Leo 275; Ro 21-8837; Estradiol 3-(bis(2-chloroethyl)carbamate) ester; Estra-1,3,5(10)-triene-3,17β-diol 3-(bis(2-chloroethyl)carbamate) ester |
Drug class | Chemotherapeutic agent; Estrogen; Estrogen ester |
ATC code | |
Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.019.161 |
Chemical and physical data | |
Formula | C23H31Cl2NO3 |
Molar mass | 440.41 g·mol−1 |
3D model (JSmol) | |
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Estramustine (INN , USAN , BAN ) is an estrogen and cytostatic antineoplastic agent which was never marketed.[1][2] It is an estrogen ester – specifically, the C3 normustine ester of estradiol – and acts in part as a prodrug of estradiol in the body.[1][2] Estramustine phosphate, the C17β phosphate ester of estramustine and a prodrug of estramustine, estromustine, estradiol, and estrone, is marketed and used in the treatment of prostate cancer.[1][2]
See also
- Estradiol mustard
- List of hormonal cytostatic antineoplastic agents
- List of estrogen esters § Estradiol esters
References
- ^ a b c Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 502–. ISBN 978-1-4757-2085-3.
- ^ a b c Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 406–. ISBN 978-3-88763-075-1.