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{{Short description|Chemical compound}} |
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{{Drugbox |
{{Drugbox |
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<!--Chemical data--> |
<!--Chemical data--> |
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| C=16 | H=19 | Br=1 | N=2 |
| C=16 | H=19 | Br=1 | N=2 |
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| molecular_weight = 319.24 g/mol |
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| smiles = Brc1ccc(cc1)[C@@H](c2ncccc2)CCN(C)C |
| smiles = Brc1ccc(cc1)[C@@H](c2ncccc2)CCN(C)C |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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'''Dexbrompheniramine''' is an [[antihistamine]] with [[anticholinergic]] properties<ref>{{cite journal | vauthors = Löfkvist T | title = A comparative evaluation of oral decongestants in the treatment of vasomotor rhinitis | journal = The Journal of International Medical Research | volume = 6 | issue = 1 | pages = 56–60 | year = 1978 | pmid = 627306 | doi = 10.1177/030006057800600110 | s2cid = 39205584 }}</ref> used to treat [[allergy|allergic]] conditions such as [[hay fever]] or [[urticaria]]. It is the pharmacologically active dextrorotatory isomer of [[brompheniramine]]. It was formerly marketed in combination with [[pseudoephedrine]] under the name [[Drixoral]] in the US and Canada. It is an alkylamine antihistamine. |
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'''Dexbrompheniramine''' is an [[antihistamine]] with [[anticholinergic]] properties<ref>{{Cite journal |
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| last1 = Löfkvist | first1 = T. |
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| title = A comparative evaluation of oral decongestants in the treatment of vasomotor rhinitis |
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| journal = The Journal of international medical research |
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| volume = 6 |
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| issue = 1 |
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| pages = 56–60 |
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| year = 1978 |
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| pmid = 627306 |
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| doi = 10.1177/030006057800600110 |
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}}</ref> used to treat [[allergy|allergic]] conditions such as [[hay fever]] or [[urticaria]]. It is the pharmacologically active dextrorotatory isomer of [[brompheniramine]]. It was formerly marketed in combination with [[pseudoephedrine]] under the name [[Drixoral]] in the US and Canada. |
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Dexbrompheniramine is a first generation antihistamine that reduces the effects of the [[neurotransmitter]] [[histamine]] in the body; sneezing, itching, watery eyes, and runny nose. |
Dexbrompheniramine is a first generation antihistamine that reduces the effects of the [[neurotransmitter]] [[histamine]] in the body; sneezing, itching, watery eyes, and runny nose. |
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== Interactions == |
== Interactions == |
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MAO inhibitors within 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. |
MAO inhibitors within 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. |
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Potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K). |
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Drinking alcohol can increase side effects of dexbrompheniramine. |
Drinking alcohol can increase side effects of dexbrompheniramine. |
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== |
==References== |
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{{Reflist}} |
{{Reflist}} |
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==External links== |
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*{{Commonscatinline}} |
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{{Antihistamines}} |
{{Antihistamines}} |
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[[Category:Enantiopure drugs]] |
[[Category:Enantiopure drugs]] |
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[[Category:H1 receptor antagonists]] |
[[Category:H1 receptor antagonists]] |
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[[Category: |
[[Category:Bromobenzene derivatives]] |
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[[Category: |
[[Category:2-Pyridyl compounds]] |
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{{respiratory-system-drug-stub}} |
{{respiratory-system-drug-stub}} |
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{{stereochemistry-stub}} |
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{{Amine-stub}} |
Revision as of 02:32, 15 April 2024
Clinical data | |
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Trade names | Drixoril, Conex, Dixaphedrine |
AHFS/Drugs.com | Multum Consumer Information |
Routes of administration | Oral |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Elimination half-life | 25 hours |
Identifiers | |
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CAS Number | |
PubChem CID | |
IUPHAR/BPS | |
DrugBank | |
ChemSpider | |
UNII | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.004.595 |
Chemical and physical data | |
Formula | C16H19BrN2 |
Molar mass | 319.246 g·mol−1 |
3D model (JSmol) | |
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(what is this?) (verify) |
Dexbrompheniramine is an antihistamine with anticholinergic properties[1] used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of brompheniramine. It was formerly marketed in combination with pseudoephedrine under the name Drixoral in the US and Canada. It is an alkylamine antihistamine.
Dexbrompheniramine is a first generation antihistamine that reduces the effects of the neurotransmitter histamine in the body; sneezing, itching, watery eyes, and runny nose.
Interactions
MAO inhibitors within 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Drinking alcohol can increase side effects of dexbrompheniramine.
References
External links
- Media related to Dexbrompheniramine at Wikimedia Commons