Chetco may refer to:
- Chetco (tribe) - a group of Native Americans who lived in southwestern Oregon in the United States
- Chetco River - a river named for the tribe, flowing to the Pacific Ocean in Curry County, Oregon in the United States
- Chetco Peak - a mountain near the source of the Chetco River in Oregon in the United States
- Chetco effect - also known as the Brookings effect, a weather pattern off the mouth of the Chetco River at the city of Brookings on the Oregon coast