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Revision as of 22:52, 30 November 2010
In biology a cancer cell is any particular cell "that is part of a malignant tumour [1] Although cancer cells can be quite common in a person they are only malignant when the other cells (particularly Natural killer cells) fail to recognize and/or destroy them [2].In the past a common belief was that cancer Cancer cells failed to be recognized and destroyed because of a weakness in the immune system. However, more recent recent has shown that cancer is instead caused by the lack of particular co-stimulated molecules that aid in the way antigens react with lymphocytes [3].
Causes
By researching stem cells scientists have suggested that "Too Much SP2 Protein" may turn "Stem Cells Into 'Evil Twin' Cancer Cells". [4] Other issues thought to play a role in the spread of cancer include Viruses,Immune system Issues, Body Weight, Physical activity, Genetics, Environment,and Age [5].
However, a lack of particular co-stimulated molecules that aid in the way antigens react with lymphocytes can impair the Natural Killer Cells ability and ultimately cause cancer [6]
Pathology
Natural Killer cells are thought to use a duel receptor system when they determine whether or not to kill human cells . If a cell is under stress , turning into tumors,or infected molecules including MICA and MICB are produced to put on the surface of the cell. [7] These work to detect and kill cancer cells [8].
Discovery
Although known descriptions of cancer go back to ancient Egypt as far back as 1600BC and the the understanding was significantly advanced during the Renaissance period Sir Rudolf Virchow a German Biologist and Politician is generally credited with discovering the first cancer cells. As Giovanni Morgagni had linked autopsy findings seen with the unaided eye with the clinical course of illness, so Virchow correlated the microscopic pathology [9].
Further Research
Oncologists have discovered various enzymes and proteins that seem to aid in the fight to cure cancer. Examples include ...
See Also
- Apoptosis
- BRCA1
- Cancer
- Carcinogen
- Epidemiology of cancer
- Natural killer cell
- Oncology
- Oncologists
- Tumors
External Links
References
- ^ http://wordnetweb.princeton.edu/perl/webwn?s=cancer%20cell
- ^ http://student.ccbcmd.edu/courses/bio141/lecguide/unit4/innate/nkcell.html
- ^ http://www.research.uky.edu/odyssey/fall99/cancerkllers.html
- ^ http://www.sciencedaily.com/releases/2010/10/101027151209.htm
- ^ http://www.cancerhelp.org.uk/about-cancer/causes-symptoms/causes/what-causes-cancer
- ^ http://www.research.uky.edu/odyssey/fall99/cancerkllers.html
- ^ http://student.ccbcmd.edu/courses/bio141/lecguide/unit4/innate/nkcell.html
- ^ http://student.ccbcmd.edu/courses/bio141/lecguide/unit5/humoral/abydefense/adcc/adcc.html
- ^ http://www.uib.no/med/avd/miapr/arvid/MOD2/Arvid/Patofysiologi/history_of_cancer.pdf
- ^ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908063/
- ^ http://www.cancer.org/Cancer/CancerBasics/TheHistoryofCancer/index
- ^ http://wordnetweb.princeton.edu/perl/webwn?s=cancer%20cell