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Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'ChEBI'). |
Updating {{drugbox}} (no changed fields - added verified revid - updated 'DrugBank_Ref', 'ChEBI_Ref') per Chem/Drugbox validation (report errors or [[u |
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{{drugbox |
{{drugbox |
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| verifiedrevid = |
| verifiedrevid = 443390851 |
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| IUPAC_name = Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate |
| IUPAC_name = Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate |
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| image = Anileridine.svg |
| image = Anileridine.svg |
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| ATC_suffix = AH05 |
| ATC_suffix = AH05 |
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| ATC_supplemental = |
| ATC_supplemental = |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| ChEBI = 61203 |
| ChEBI = 61203 |
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| PubChem = 8944 |
| PubChem = 8944 |
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| ChemSpiderID=8600 |
| ChemSpiderID=8600 |
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| smiles = O=C(OCC)C3(c1ccccc1)CCN(CCc2ccc(N)cc2)CC3 |
| smiles = O=C(OCC)C3(c1ccccc1)CCN(CCc2ccc(N)cc2)CC3 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = APRD00741 |
| DrugBank = APRD00741 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
| KEGG_Ref = {{keggcite|correct|kegg}} |
Revision as of 19:31, 6 August 2011
Clinical data | |
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Routes of administration | Tablets, injection |
ATC code | |
Legal status | |
Legal status |
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Pharmacokinetic data | |
Protein binding | > 95% |
Metabolism | Hepatic |
Identifiers | |
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CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C22H28N2O2 |
Molar mass | 352.47 g/mol g·mol−1 |
3D model (JSmol) | |
Melting point | 83 °C (181 °F) |
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(verify) |
Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by Merck & Co. in the 1950s[1]. It differs from meperidine (Demerol) in that the N-methyl group of meperidine is replaced by an N-aminophenethyl group, which increases its analgesic activity.
Anileridine is no longer manufactured in the US or Canada.[2]
Administration
Pharmacokinetics
Anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours.[4] It is mostly metabolized by the liver.
References
- ^ US Patent 2897204
- ^ "Discontinued Prescription Drug Products". Canadian Pharmacists' Association. Retrieved 28 July 2008.
- ^ "Pharmaceutical Information - LERITINE". RxMed. Retrieved 16 June 2010.
- ^ "Anileridine Consumer Information". MedicineNet. Retrieved 28 July 2008.