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| verifiedrevid = 443390851 |
| verifiedrevid = 443390851 |
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| IUPAC_name = Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate |
| IUPAC_name = Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate |
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| image = Anileridine.svg |
| image = Anileridine.svg |
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<!--Clinical data--> |
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| tradename = |
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| Drugs.com = {{drugs.com|monograph|buprenorphine-hydrochloride}} |
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<!--Pharmacokinetic data--> |
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<!--Identifiers--> |
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| CASNo_Ref = {{cascite|correct|CAS}} |
| CASNo_Ref = {{cascite|correct|CAS}} |
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| CAS_number = 144-14-9 |
| CAS_number = 144-14-9 |
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| ATC_prefix = N01 |
| ATC_prefix = N01 |
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| ATC_suffix = AH05 |
| ATC_suffix = AH05 |
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| ATC_supplemental = |
| ATC_supplemental = |
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| PubChem = 8944 |
| PubChem = 8944 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = APRD00741 |
| DrugBank = APRD00741 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D02941 |
| KEGG = D02941 |
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<!--Chemical data--> |
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| molecular_weight = 352.47 g/mol |
| molecular_weight = 352.47 g/mol |
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| melting_point = 83 |
| melting_point = 83 |
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Revision as of 22:05, 30 August 2011
Clinical data | |
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AHFS/Drugs.com | Monograph |
Routes of administration | Tablets, injection |
ATC code | |
Legal status | |
Legal status |
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Pharmacokinetic data | |
Protein binding | > 95% |
Metabolism | Hepatic |
Identifiers | |
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CAS Number | |
PubChem CID | |
DrugBank | |
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KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C22H28N2O2 |
Molar mass | 352.47 g/mol g·mol−1 |
3D model (JSmol) | |
Melting point | 83 °C (181 °F) |
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(verify) |
Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by Merck & Co. in the 1950s[1]. It differs from meperidine (Demerol) in that the N-methyl group of meperidine is replaced by an N-aminophenethyl group, which increases its analgesic activity.
Anileridine is no longer manufactured in the US or Canada.[2]
Administration
Pharmacokinetics
Anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours.[4] It is mostly metabolized by the liver.
References
- ^ US Patent 2897204
- ^ "Discontinued Prescription Drug Products". Canadian Pharmacists' Association. Retrieved 28 July 2008.
- ^ "Pharmaceutical Information - LERITINE". RxMed. Retrieved 16 June 2010.
- ^ "Anileridine Consumer Information". MedicineNet. Retrieved 28 July 2008.