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{{short description|Australian oncologist}} |
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'''Judith Clements''' is an Australian |
'''Judith Ann Clements''' {{post-nominals|country=AUS|AC|FAHMS}} is an Australian academic and educator, specializing in Kallikrein proteases in prostate and ovarian cancers. Clements is the scientific director at the Australian Prostate Cancer Research Centre – Queensland and was head of the Cancer Research Program at the Institute of Health and Biomedical Innovation (IHBI) of [[Queensland University of Technology]] at the [[Translational Research Institute (Australia)]] from 1997–2014.<ref>{{cite web|title=Distinguished Professor Judith Clements profile|url=http://staff.qut.edu.au/staff/clements|website=staff.qut.edu.au|publisher=Queensland University of Technology|accessdate=7 August 2014}}</ref> |
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==Research== |
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The Cancer Research Program led by Clements at QUT-IHBI, aims to more clearly understand the molecular and cellular basis for the development, progression, and metastasis of solid tumours.<ref>{{cite web|title=Distinguished Professor Judith Clements profile|url=http://staff.qut.edu.au/staff/clements|website=staff.qut.edu.au|publisher=Queensland University of Technology|accessdate=7 August 2014}}</ref> |
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Clements' research specialises in ovarian and prostate cancers, particularly focusing on the Kallikrein proteases and their utility as biomarkers and therapeutic targets for cancer progression. Clements has publications in over 190 publications scientific journals.<ref>{{cite web|title=TRI Staff Profile: Judith Clements|url=https://www.tri.edu.au/staff/judith-clements|website=http://www.tri.edu.au/}}</ref><ref>{{cite web|title=Judith Clements Publications|url=http://www.ncbi.nlm.nih.gov/pubmed?term=Clements%20JA|website=www.ncbi.nlm.nig.gov/|accessdate=6 January 2015}}</ref> |
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Clements is currently organising the 9th General Meeting of the International Proteolysis Society, to be held in [[Penang]], [[Malaysia]] from October 4-5 2015.<ref>{{cite web|title=International Protease Society: Quick Cuts|url=http://www.protease.org/QuickCuts/QuickCuts_2014_Jan.pdf|website=http://www.protease.org/|publisher=International Protease Society|accessdate=14 August 2014}}</ref> |
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⚫ | :''"The primary interest of my group within the Hormone Dependent Cancer Program is the tissue kallikrein family of serine proteases. Our group was one of three worldwide that identified and characterised the expanded human tissue kallikrein gene locus on chromosome 19q13.4 in 1999. Since that time, our research has focused on defining the roles of particular kallikreins, and their variant forms, in hormone dependent cancers such as prostate, ovarian and endometrial cancer. We have used conventional/real time PCR and immunohistochemistry to determine the association of kallikrein expression with clinical disease to determine their usefulness as biomarkers for detection, prognostic outcome and therapeutic approaches. We are also utilizing over-expression and knockout systems to determine the effect of kallikrein expression in cancer cell lines at the cell biology level. Other studies in progress are directed to understanding the structure/function of the kallikreins, their substrate specificity and in vivo interacting proteins and genomic regulation. Other protease research interests are the type 2 trans membrane serine proteases (with Dr John Hooper) and the ADAMs (with Prof Adrian Herington and Dr Dimitri Odorico).''<ref>{{cite web|title=Australian Protease Network – Professor Judith Clements|url=http://www.protease.net.au/index.php?id=23&pid=60|accessdate=6 January 2015}}</ref> |
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==Education== |
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Clements completed her [[PhD]] in [[Endocrinology]] at [[Monash University]] in 1989, her Master of Applied Science in 1983, after completing her Bachelor of Applied Science in 1982 and Diploma of Laboratory Technology in 1969 at the [[Royal Melbourne Institute of Technology]].<ref>{{cite web|title=Judith Clements|url=http://www.australianprostatecentre.org/about-us/our-people/judith-clements|website=australianprostatecentre.org|publisher=Australian Prostate Cancer Research Centre, Queensland|accessdate=6 January 2015}}</ref> |
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* 2017 Fellow of the [[Australian Academy of Health and Medical Sciences]]<ref>{{Cite web|last=|first=|date=October 2017|title=AAHMS Announces its Second Scientific Meeting and Induction of New Fellows|url=https://aahms.org/wp-content/uploads/2017/10/20171019-AAHMS-Media-Release_2017-New-Fellows-Announced1.pdf|archive-url=|archive-date=|access-date=2020-12-08|website=Australian Academy of Health and Medical Sciences}}</ref> |
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*2015 Companion of the Order of Australia<ref>{{cite web|title=Queen's Birthday honours|url=https://www.qut.edu.au/institute-of-health-and-biomedical-innovation/about/news/news?news-id=90717| |
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⚫ | :''"The primary interest of my group within the Hormone Dependent Cancer Program is the tissue kallikrein family of serine proteases. Our group was one of three worldwide that identified and characterised the expanded human tissue kallikrein gene locus on chromosome 19q13.4 in 1999. Since that time, our research has focused on defining the roles of particular kallikreins, and their variant forms, in hormone dependent cancers such as prostate, ovarian and endometrial cancer. We have used conventional/real time PCR and immunohistochemistry to determine the association of kallikrein expression with clinical disease to determine their usefulness as biomarkers for detection, prognostic outcome and therapeutic approaches. We are also utilizing over-expression and knockout systems to determine the effect of kallikrein expression in cancer cell lines at the cell biology level. Other studies in progress are directed to understanding the structure/function of the kallikreins, their substrate specificity and in vivo interacting proteins and genomic regulation. Other protease research interests are the type 2 trans membrane serine proteases (with Dr John Hooper) and the ADAMs (with Prof Adrian Herington and Dr Dimitri Odorico).''<ref>{{cite web|title=Australian Protease Network |
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accessdate=4 December 2020}}</ref> |
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== Education == |
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* 2011 Queensland University of Technology Vice Chancellor's Award for Research Excellence<ref>{{cite web|title=Judith Clements|url=http://www.australianprostatecentre.org/about-us/our-people/judith-clements|website=australianprostatecentre.org|publisher=Australian Prostate Cancer Research Centre, Queensland|accessdate=20 December 2015}}</ref> |
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* 2011 Queensland University of Technology Vice Chancellor’s Award for Research Excellence<ref>{{cite web|title=Judith Clements|url=http://www.australianprostatecentre.org/about-us/our-people/judith-clements|website=http://www.australianprostatecentre.org|publisher=Australian Prostate Cancer Research Centre, Queensland}}</ref> |
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* 2005 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting |
* 2005 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting |
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* 2001 Queensland University of Technology Faculty of Science Distinguished Award for Excellence in Research |
* 2001 Queensland University of Technology Faculty of Science Distinguished Award for Excellence in Research |
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* 1998 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting |
* 1998 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting |
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* 1995 National Health and Medical Research Council Senior Research Fellowship |
* 1995 National Health and Medical Research Council Senior Research Fellowship |
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* 1991 Prize for an |
* 1991 Prize for an "Outstanding Presentation", Kinin 91, International Conference on Kallikreins and Kinins, Munich, Germany.<ref>{{cite web|title=Judith Clements|url=http://www.australianprostatecentre.org/about-us/our-people/judith-clements|website=australianprostatecentre.org|publisher=Australian Prostate Cancer Research Centre, Queensland|accessdate=20 December 2015}}</ref> |
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==References== |
==References== |
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{{reflist}} |
{{reflist}} |
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== |
==External links== |
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* [http://www.tri.edu.au/staff/judith-clements|Translational Research Institute staff profile] |
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* [http://staff.qut.edu.au/staff/clements|Queensland University of Technology staff profile] |
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* [http://www.aus-canprostatealliance.org/Members/j.clements-40qut.edu.au|Australian-Canadian Prostate Cancer Research Alliance] |
* [http://www.aus-canprostatealliance.org/Members/j.clements-40qut.edu.au|Australian-Canadian Prostate Cancer Research Alliance] |
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* [http://www.australianprostatecentre.org/about-us/our-people/judith-clements|Australian Prostate Cancer Research Centre profile] |
* [http://www.australianprostatecentre.org/about-us/our-people/judith-clements|Australian Prostate Cancer Research Centre profile] |
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* [https://au.linkedin.com/pub/judith-clements/a0/976/406|LinkedIn Profile] |
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{{Authority control}} |
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{{Persondata |
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| NAME = Clements, Judith |
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| ALTERNATIVE NAMES = |
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| SHORT DESCRIPTION = Australian oncologist |
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| DATE OF BIRTH = |
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| PLACE OF BIRTH = |
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| DATE OF DEATH = |
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}} |
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{{DEFAULTSORT:Clements, Judith}} |
{{DEFAULTSORT:Clements, Judith}} |
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[[Category:Living people]] |
[[Category:Living people]] |
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[[Category: |
[[Category:Place of birth missing (living people)]] |
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[[Category:Year of birth missing (living people)]] |
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[[Category:Australian medical researchers]] |
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[[Category:Companions of the Order of Australia]] |
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[[Category:Fellows of the Australian Academy of Health and Medical Sciences]] |
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[[Category:RMIT University alumni]] |
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[[Category:Monash University alumni]] |
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[[Category:Cancer researchers]] |
Latest revision as of 16:13, 27 September 2023
Judith Ann Clements AC FAHMS is an Australian academic and educator, specializing in Kallikrein proteases in prostate and ovarian cancers. Clements is the scientific director at the Australian Prostate Cancer Research Centre – Queensland and was head of the Cancer Research Program at the Institute of Health and Biomedical Innovation (IHBI) of Queensland University of Technology at the Translational Research Institute (Australia) from 1997–2014.[1]
Research
The Cancer Research Program led by Clements at QUT-IHBI, aims to more clearly understand the molecular and cellular basis for the development, progression, and metastasis of solid tumours.[2]
Clements has commented on her research, stating:
- "The primary interest of my group within the Hormone Dependent Cancer Program is the tissue kallikrein family of serine proteases. Our group was one of three worldwide that identified and characterised the expanded human tissue kallikrein gene locus on chromosome 19q13.4 in 1999. Since that time, our research has focused on defining the roles of particular kallikreins, and their variant forms, in hormone dependent cancers such as prostate, ovarian and endometrial cancer. We have used conventional/real time PCR and immunohistochemistry to determine the association of kallikrein expression with clinical disease to determine their usefulness as biomarkers for detection, prognostic outcome and therapeutic approaches. We are also utilizing over-expression and knockout systems to determine the effect of kallikrein expression in cancer cell lines at the cell biology level. Other studies in progress are directed to understanding the structure/function of the kallikreins, their substrate specificity and in vivo interacting proteins and genomic regulation. Other protease research interests are the type 2 trans membrane serine proteases (with Dr John Hooper) and the ADAMs (with Prof Adrian Herington and Dr Dimitri Odorico).[3]
Education
Clements completed her PhD in Endocrinology at Monash University in 1989, her Master of Applied Science in 1983, after completing her Bachelor of Applied Science in 1982 and Diploma of Laboratory Technology in 1969 at the Royal Melbourne Institute of Technology.[4]
Awards
- 2017 Fellow of the Australian Academy of Health and Medical Sciences[5]
- 2015 Companion of the Order of Australia[6]
- 2012 Women in Technology (WiT) Biotech Outstanding Achievement Award[7]
- 2011 Queensland University of Technology Vice Chancellor's Award for Research Excellence[8]
- 2007 Gold Medal, E.K.Frey–E.Werle Foundation for pioneering work in the Kallikrein field[9]
- 2006 Research featured in "Ten Of The Best" National Health and Medical Research Council funded health and medical research successes[10]
- 2005 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting
- 2001 Queensland University of Technology Faculty of Science Distinguished Award for Excellence in Research
- 2000 National Health and Medical Research Council Principal Research Fellowship
- 2000 Silver Medal and Honorary Membership of the E.K.Frey–E.Werle Foundation (awarded at the International Conference, Kinin 2000, Munich)
- 1998 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting
- 1995 National Health and Medical Research Council Senior Research Fellowship
- 1991 Prize for an "Outstanding Presentation", Kinin 91, International Conference on Kallikreins and Kinins, Munich, Germany.[11]
References
- ^ "Distinguished Professor Judith Clements profile". staff.qut.edu.au. Queensland University of Technology. Retrieved 7 August 2014.
- ^ "Distinguished Professor Judith Clements profile". staff.qut.edu.au. Queensland University of Technology. Retrieved 7 August 2014.
- ^ "Australian Protease Network – Professor Judith Clements". Retrieved 6 January 2015.
- ^ "Judith Clements". australianprostatecentre.org. Australian Prostate Cancer Research Centre, Queensland. Retrieved 6 January 2015.
- ^ "AAHMS Announces its Second Scientific Meeting and Induction of New Fellows" (PDF). Australian Academy of Health and Medical Sciences. October 2017. Retrieved 8 December 2020.
- ^ "Queen's Birthday honours". Retrieved 4 December 2020.
- ^ "WiT Award Winners 2012". wit.org.au. Women in Technology. Retrieved 6 January 2015.
- ^ "Judith Clements". australianprostatecentre.org. Australian Prostate Cancer Research Centre, Queensland. Retrieved 20 December 2015.
- ^ Biol. Chem., Vol. 389, pp. 621–622, June 2008
- ^ "10 of the Best 2006". nhmrc.gov.au. Retrieved 6 January 2015.
- ^ "Judith Clements". australianprostatecentre.org. Australian Prostate Cancer Research Centre, Queensland. Retrieved 20 December 2015.