Psion or Psions may refer to:
Fiction
- Psion (comics), an alien race in DC Comics
Literature
- Psion, a fictitious "unit of mental energy" in the 1951 novella The Greatest Invention by Jack Williamson
- Psion, a person with psionic abilities
- Psion, a 1982 novel by Joan D. Vinge
- Psion (想子), a fictional substanceless particle and psychic phenomenon, the basis of magic in The Irregular at Magic High School
- Rhon psion, or Ruby psion, a group of telepaths in the Saga of the Skolian Empire novel series
Video gaming
- Psion (role-playing games) a character class in role-playing games
- Psion (Dungeons & Dragons), a character class in Dungeons & Dragons
- Psions (Freedom City), a supervillain team in Freedom City
- Psions, a fictional group in the game Adventure!
- Psion, an alien species with extraordinary powers assimilated by the Cabal Empire in the video games Destiny and Destiny 2
- Psion, a category of enemies in the video game Into the Breach
Science
- Psion, the J/ψ meson (discovered 1974)
Computing
- Psion (company), a manufacturer of handheld computer devices